Sickle cell anemia is an inherited form of blood disorder. Sickle cell anemia changes your red blood cells from round, flexible discs to stiff, sticky sickled cells. Sickled cells prevent red blood cells from doing their job of transporting oxygen throughout the body. Sickled cells also have a shorter lifespan than normal red blood cells leading breakdown of red cells and anemia.
People with sickle cell anemia continue to face potentially fatal medical complications.
According to Best doctor for treatment of Sickle cell anemia in Delhi People who have sickle cell anemia get it from their biological parents. The gene that aids in the production of normal red blood cells mutates or changes in sickle cell anemia. People with sickle cell anemia inherit the mutated hemoglobin protein gene from both biological parents. People with sickle cell trait inherit the mutated gene from one biological parent.
Symptoms of sickle cell anemia usually appear as early as six months of age. They vary from person to person and change over time. Among the signs and symptoms are:
Both parents must carry the sickle cell gene for their child to be born with sickle cell anemia. People of African, Mediterranean, and Middle Eastern descent are the most commonly affected by sickle cell anemia in the United States. It is widespread among the tribal population in India. In India, the state of Chattissgarh, Odisha, Jharkhand, Madhya Pradesh, upper Assam has higher number of sickle cell anemia patients.
Seeing a genetic counsellor before trying to conceive can help you understand your risk of having a child with sickle cell anemia if you carry the sickle cell trait. A genetic counsellor can also discuss the preventive measures, and reproductive options.
A blood test called HPLC can detect the type of haemoglobin that causes sickle cell anemia. This blood test is part of routine test during pregnancy in most of the major centres in India. Its always advisable to do a HPLC tests of both of the partners before trying to conceive.
The goal of sickle cell anemia treatment is to avoid pain episodes, relieve symptoms, and prevent complications. Medication and blood transfusions may be used as treatments. Hematopoietic stem cell transplantation, commonly known as bone marrow transplant is a curative treatment option for some children and teenagers who develop repeated painful episodes and acute stroke.
The use of medications on a daily basis reduces the frequency of
painful episodes and may reduce the need for blood transfusions and hospitalizations.
Some new targeted medications are now available to be used to treat sickle cell disease in adults and children over the age of twelve. When taken orally, this medication can reduce the risk of anemia while also improving blood flow throughout the body.
Medication for pain relief is used during sickle cell pain episodes, your doctor may prescribe narcotics to help relieve pain and good hydration is very important to prevent pain episodes.